The intake in an appropriate dose (20–35 g/day for healthy adults) of dietary fiber (DF) has long been linked to reduction of metabolic diseases incidence, including diabetes, cardiovascular disease and obesity, among others, due to its capacity to lower blood cholesterol and C Reactive Protein (CRP), to attenuate glucose absorption and to improve insulin response [1,2,3]. The gene discussed is CRP; the disease is cardiovascular disorder.