First, there are special features that explain tumor selectivity of NDV [30]: (i) Targeting the oncogenic protein Rac1, (ii) tumor-selective virus replication, (iii) promotion of virus propagation via syncytia, autophagy, and exosomes, (iv) tumor-selective oncolysis and (v) tumor-selective induction of immunogenic cell death. The gene discussed is PROS1; the disease is neoplasm.