One of the latest investigations to clarify the mechanism of kaempferol as an anticancer drug against breast tumors was carried out by Zhu et al. The authors mentioned that kaempferol induced apoptosis and DNA damage in MDA-MB-231 cancer cells by the upregulation of the phosphorylated form of the H2A histone family member X (γH2AX), caspase 3, caspase 9, and the protein serine/threonine kinase (p-ATM) [73]. Here, CASP3 is linked to cancer.