When 96 GBM patients were stratified into the SOH or AH subgroups (Figure 2C), Kaplan–Meier plots showed a significant association between the gene signature and overall survival (p = 0.027, Figure 2D), strongly supporting the robustness of the signature and association of YAP1/TAZ activation with poor prognosis in GBM. The gene discussed is YAP1; the disease is glioblastoma.