The 7 miRNAs that were significantly upregulated in cancer-infiltrated LVs, and the 7 miRNAs that were significantly down-regulated in inflamed LVs have known involvement in various pathways related to the TGFβ-pathway, fatty acid biosynthesis, proteoglycans in cancer, glycosaminoglycan synthesis and glycan biosynthesis as well as the extracellular matrix receptor interactions pathway and adherens junction pathway (Table 6). The gene discussed is TGFB1; the disease is cancer.