AKT1 and bronchiolitis obliterans syndrome: Akt phosphorylation (Ser-473) of cardiac muscle was significantly decreased in the heart of BO mice (Control (n = 6) vs. BO (n = 4): 100 ± 15 vs. 70 ± 13%, P = 1.0 x 10−2 by the Tukey-Kramer post hoc test).