QPRT and breast cancer: Transfection with shRNA-DSCAM-AS1 decreased DSCAM-AS1 expression in MCF-7 and T47D cells (P < 0.01, Figure 4F), which resulted in decreased DCTPP1 and QPRT mRNA and protein levels (P < 0.05 or P < 0.01) in ER-positive BC cells (Figure 4F and 4H).