Given the recent finding, that PKR is capable of phosphorylating the PD‐associated Serine 129 α‐synuclein residue and the fact that α‐synuclein and tau both belong to the group of intrinsically disordered proteins and both become extensively phosphorylated in distinctive neurodegenerative disorders (47, 53), we sought to investigate a potential role for a direct influence of PKR on tau phosphorylation. Here, EIF2AK2 is linked to Parkinson disease.