SLC8A1 and Parkinson disease: Unlike the increases of circSLC8A1 in the PD brain (P = 0.025, Fig 44B), the levels of the linear SLC8A1 mRNA showed no significant change (P = 0.118, Fig 44C), as we validated by qRT–PCR from a larger pool of 18 controls and 24 PD SN samples (some of which were not sequenced).