CircSLC8A1, which is significantly upregulated in the PD SN (Fig 44A and B), originates from the neuronally expressed SLC8A1 gene, which encodes a Ca2+/Na+ transporter that contributes to balancing cytoplasmic Ca2+ levels and the surveillance over Ca2+‐dependent neurotransmission (He et al, 2009). Here, SLC8A1 is linked to Parkinson disease.