Although the pathogenesis of pSS is not fully understood yet, activation of exocrine gland epithelium cells is thought to lead to the release of pro‐inflammatory cytokines such as IFNα and IFNβ (both type I IFN), IL‐7 and BAFF, and chemokines (Retamozo et al, 2018). Here, TNFSF13B is linked to peeling skin syndrome.