In NwCRC patients numerous pathway terms associated with metabolic processes (e.g., One-carbon metabolism, Purine metabolism, Cysteine/Methionine metabolism), lipid metabolism (e.g., Fatty acyl-coA biosynthesis, AMPK, and SREBP signaling) and pathways involved in cancer (e.g., Signaling by FGFR1 in disease, Pathway in clear cell renal cell carcinoma) were obtained (Figure 6A). Here, FGFR1 is linked to clear cell renal carcinoma.