Candidate transcripts were selected among those DEL and DEM found to be shared between cancer and obese conditions (e.g., LINC01106, LINC00968, SNHG16, miR-125a-5p, miR-193b-3p, miR-1247-5p), along with those of ncRNAs specific for CRC or obese subjects (e.g., XIST, H19, MINCR, miR-29b, miR-125b-1-3p, miR-181d-5p), on the basis of their relevance in the described regulatory networks. The gene discussed is XIST; the disease is cancer.