In order to explore the effect of MCM3AP-AS1 on the biological characteristics of ccRCC cells by regulating DPP4, Caki-1 and 786-O cells were co-transfected with oe-NC and sh-NC, oe-MCM3AP-AS1 and sh-NC, oe-MCM3AP-AS1 and sh-DPP4, respectively. Here, DPP4 is linked to nonpapillary renal cell carcinoma.