Hence, the significant associations between the classification output and the Aβ, tau, PGRS indices, and the length of time for MCI patients to convert to AD further provided a solid neurobiological basis for potential clinical applications of 3DAN.[57, 58] And our further analyses showed that 5/6 of these correlations are stronger in 3DAN model than that in SVM (Figure S6, Supporting Information) highlighted the effectiveness of the attention mechanism for key regions identification and early classification. This evidence concerns the gene MAPT and Alzheimer disease.