In addition, the authors used immunostaining to show high levels of AcH3 in 83% of dopaminergic (tyrosine hydroxylase (TH)-immunopositive) midbrain neurons in the PD SNpc, which was not found in non-dopaminergic cells in these samples, and was only seen in 2% of dopaminergic neurons in the SNpc from controls. The gene discussed is TH; the disease is Parkinson disease.