Abnormalities of thyroid function have a variety of clinical spectrums and it is a common clinical problem, many patients presented with subclinical derangements of the thyroid functions and are diagnosed on the basis of thyroid hormone evaluation or abnormal results of other investigations including blood parameters or lipid abnormalities, cardiac dysfunction, atherosclerosis, and many other clinical manifestations [[3], [4], [5], [6], [7]]. This evidence concerns the gene TG and thyroid gland disorder.