IGF1 and hepatocellular carcinoma: Though it has been found that IGF signaling is associated with Wnt signaling in particular cell types such as spermatogonial (Safian et al., 2018), satellite (Siegle et al., 2018), hepatoma cells (Desbois-Mouthon et al., 2001) and chondrocytes (Wang et al., 2010b), the relation between Wnt signaling and IGF-I has not been identified in granulosa cells.