TNF and ischemic stroke: According to the literature and KEGG enrichment analysis, the pharmacological effects of musk for ischemic stroke were associated with TNF signaling pathway, estrogen signaling pathway, prolactin signaling pathway, neurotrophin signaling pathway, T-cell receptor signaling pathway, cAMP signaling pathway, FoxO signaling pathway, HIF-1 signaling pathway, nonalcoholic fatty liver disease (NAFLD), Rap1 signaling pathway, and so on (the details are depicted in Table 3).