Significant contralesional recruitment was observed in patients age 50 or older (p = 0.04), had less than 10 months between scans (p = 0.05), tumor volume ≥ 16 cm3 (p = 0.003), growth velocities greater than 0.7 cm3/month (p = 0.01), tumors < 2 cm from M1 (p = 0.04), having a deficit on the first clinical exam (p = 0.05), and increased SMA activation (p = 0.01). Here, SMN1 is linked to neoplasm.