Finally, we introduced a case study, enhancer: chr1:1186391–1186507 ∼ miR-200a was highly relevant to the survival of thyroid cancer patients and a cis-eQTL SNP on enhancer affected the expression of the TNFRSF18 gene, a tumor suppressor. The gene discussed is TNFRSF18; the disease is thyroid gland carcinoma.