Each SD of genetically higher WHR was associated with increased T2DM risk [3.12; 2.653–3.668], higher fasting glucose [1.087; 1.054–1.12], higher fasting insulin [1.193; 1.153–1.234], higher HOMA-IR [1.203; 1.155–1.252], and higher HbA1c [1.075; 1.056–1.095]. This evidence concerns the gene INS and type 2 diabetes mellitus.