Nevertheless, TDL might occur in patients with other atypical demyelinating syndromes such as Acute Disseminated Encephalomyelitis (ADEM), AQ4 IgG seropositive or MOG-seropositive Neuromyelitis Optica Spectrum Disorders (NMOSD), as well as other neuroinflammatory disorders, such as Neurosarcoidosis or Behçet's disease (4). This evidence concerns the gene MOG and acute disseminated encephalomyelitis.