HLA-B*15:02 is ethnically specific in CBZ-induced SJS/TEN because of the genetic background; it is comparatively high in Han Chinese, Malaysian, and Thai populations, compared with Japanese, Korean, and European populations (Alfirevic et al., 2006; Kano et al., 2008; Kaniwa et al., 2010; Chang et al., 2011; Kim et al., 2011; He et al., 2013; Aggarwal et al., 2014) (Table 1). Here, HLA-B is linked to toxic epidermal necrolysis.