We evaluated the mRNA levels of the proinflammatory cytokines such as IL-1β, IL-6, TNF-α, and COX-2 in the intestine of DSS-treated mice (IBD group), and the levels in the large intestine were increased (p < 0.05), indicating that DSS treatment obviously induced IBD (Figure 3). The gene discussed is IL6; the disease is inflammatory bowel disease.