GABBR1 and obstructive sleep apnea syndrome: Arguably, the GABBR1 variant (rs29230) had the most consistent evidence for an association with OSA-related traits in European Americans in our sample, including a significant association with increased risk for OSA in meta-analysis (OR = 1.06, p = 8.44 × 10− 3) and evidence of an association with increased wake after sleep onset (p = 1.73 × 10− 3).