. , K of Eq.(2):Mechanism of action (MOA) model: in this approach the gene expression data matrix was from the start restricted to a collection of genes representative of the mechanism of action of iniparib, which is presumed to induce oxidative stress in target cells through inhibition of the enzymes thioredoxin reductase 1 and 2 (Zachayus JL et al: Iniparib is a Cytotoxic Anti-Tumor Prodrug Bioactivated by TrxR1/2. This evidence concerns the gene TXNRD1 and neoplasm.