RPS6KA1 and breast carcinoma: Figure 1 shows a representative result for the rs3168891 genotyping with TaqMan Assay. The T allele of the rs2899849 SNP was associated with risk of breast cancer only in the homozygous state (Table 2). No association was found between rs2230394 which is located in the IBTG1 gene and the risk of breast cancer (Table 2). The T allele of SNP rs2229714 which is located in the RPS6KA1 gene was also significantly associated with increased risk of breast cancer (Table 2).