A similar mechanism (DNMT inhibition) has been demonstrated in colon cancer HCT116 cells (Yang et al., 2013), HCC Hep G2 (Nakamura et al., 2013), cholangiocarcinoma cell lines TFK-1 and HuCCT1 (Nakamura et al., 2015). The gene discussed is DNMT1; the disease is malignant colon neoplasm.