It reactivates p21Cip1/Waf1/Sdi1in HCT 116 colon cancer cells (Jiemjit et al., 2008), p27Kip1 in colon cancer SW1116 cells (Lu et al., 2007), Caco2, RKO, SW48, SW480, Colo201, Colo205, Colo320, BM314, DLD-1, and HT29 (Kikuchi et al 2002). Here, CDKN1B is linked to colonic neoplasm.