Several studies failed to investigate an increased risk of lung cancer with XPD Lys751Gln polymorphism (David-Beabes et al., 2001; Park et al., 2002), whereas other reports observed an association of lung cancer risk with variant alleles in XPD (Liang et al., 2003; Zhou et al., 2002). Here, ERCC2 is linked to lung carcinoma.