PROCR and cytomegalovirus infection: In some cases, the expression of the recognized antigen on certain target cells does not induce the respective γδ TCR, e.g., in the case of EPCR,25 EphA254 and the MHC-molecules I-E119 and HLA-A∗24:02.23 Interestingly, although identified as the antigen of a CMV-reactive γδ TCR, the expression of the EPCR is unchanged upon CMV infection.