Next, we used a public database (http://gepia.cancer-pku.cn/index.html) to detect OSBPL3 expression in a variety of tumors and normal tissues, we found that OSBPL3 expression was significantly higher than normal in 21 malignancies, including colorectal cancer (Supplementary Fig. S1B, C). This evidence concerns the gene OSBPL3 and colorectal cancer.