Bioinformatics analysis (cBioPortal for Cancer Genomics (http://www.Cbioportal.org) showed that in TCGA (Nature 2012, n = 212, Provisional, n = 220) colorectal cancer respectively, the mutant rate of OSBPL3 is only 3.8% and 3.4%, and neither gene deletion nor gene amplification was discovered. This evidence concerns the gene OSBPL3 and colorectal cancer.