In addition, both in vitro (Fig. 2c, Supplementary Fig. 8d) and in vivo (Fig. 2h, Supplementary Fig. 8d) CRISPR/Cas9 screens revealed that CTR1 (Slc31a1) is dispensable for KRAS-mutated cell fitness and tumor growth. This evidence concerns the gene SLC31A1 and neoplasm.