In our previous study (Dey et al., 2014), we reported that PanIN lesions/PDAC can arise from a unique intermediate ADM-like cellular transition; this was shown by localization of epithelial/ductal cell marker, CK-19; acinar cell marker, amylase; and PD2/Paf1 (pancreatic differentiation 2) in KC and cerulin-injected KC mouse models. The gene discussed is KRT19; the disease is keratoconus.