The top 50 diseases included “Obesity” (p = 1.24 × 10−13), “Diabetes” (p = 2.68 × 10−10), “Diabetes Mellitus, Non-Insulin-Dependent” (p = 3.79 × 10−10), and “Diabetes Mellitus” (p = 6.43 × 10−9 (Table S3)). This evidence concerns the gene INS and obesity due to melanocortin 4 receptor deficiency.