The obese group was characterized of higher TG, CRP, glucose, insulin, BMI and HOMA-IR indices, and lower HDL-Chol concentration, compared to the non-obese group, which accounts for the lack of discrepancy between the observed characteristics of both groups and the “typical” clinical picture of obesity: insulin resistance, improper distribution of body fat, dyslipidemia and the state of meta-inflammation. Here, INS is linked to obesity due to melanocortin 4 receptor deficiency.