Interaction networks build basing on genes overexpressed in recipient cells upon co-incubation with MTEX identified a variety of other exosomal molecules, apart from PD-1 and mTOR, which might affect tumor progressions, such as MET, Ras, RAF1, Mek, ERK1/2, MITF, BCL2, PI3K, Akt, KIT, JAK STAT3, or ETS1 [119]. The gene discussed is PDCD1; the disease is neoplasm.