HDGF and gastric cancer: In gastric cancer, METTL3-mediated m6A regulation plays an oncogenic role, and accelerates epithelial-mesenchymal transition (EMT) and metastasis via the METTL3/zinc finger MYM-type containing 1 (ZMYM1)/E-cadherin pathway [87], as well as the METTL13/heparin binding growth factor (HDGF)/glucose transporter 4 (GLUT4)/enolase 2 (ENO2) axis [88].