Intriguingly, another study regarding the mechanism via which YTHDF2 affects AML showed that YTHDF2 binds to the MYC mRNA, which further enhances its stability and expression, antagonizing the action of the tumor suppressor R-2-hydroxyglutarate (R-2HG) in leukemic cells [107]. This evidence concerns the gene MYC and acute myeloid leukemia.