Interestingly, other studies indicated that METTL3 boosts the translation of m6A-modified mRNAs within the CDS by releasing ribosome stalling [73], and that METTL3 might directly facilitate translation of m6A-containing mRNAs near stop codons in cancer cells without the involvement of m6A reader proteins, including YTHDF1 or YTHDF2 [74]. The gene discussed is YTHDF1; the disease is cancer.