In that report, Ang (1–7) (< 1pg/mL in healthy subjects) ranged between 80–1070 pg/mL and Ang (1–7)/Ang II ratio (~ 0.06 in healthy subjects) ranged between 0.24–1.82 [92], suggesting that ACE2 activity (and ACE2 presence in plasma samples) was significantly increased in ARDS patients as compared to healthy subjects. The gene discussed is AGT; the disease is acute respiratory distress syndrome.