As a matter of fact, various genomic biomarkers for CKD have been described in the last decade [76], including UMOD, SHROOM3 and ELMO1. UMOD encodes for a uromodulin also referred to as Tamm–Horsfall glycoprotein, a GPI-anchored glycoprotein, which is also the most abundant protein in normal urine [77]. This evidence concerns the gene UMOD and chronic kidney disease.