An increase in ectopic deposition upon CENP-A overexpression has been demonstrated in HeLa cells [12,48,137], DLD1 (colorectal adenocarcinoma) cells [12], RPE-1 cells [137] and SW480 (colorectal cancer) cells [135], using immunofluorescence, CENP-A ChIP-sequencing and CENP-A ChIP-qPCR. This evidence concerns the gene CENPA and colorectal cancer.