Importantly, HJURP is also elevated in certain cancers (Figure 5B), including breast and pancreatic cancers, where upregulation of HJURP was found to correlate with decreased survival [172], and HJURP expression level serves as an unfavorable prognostic marker in melanoma, as well as pancreatic, liver, and lung cancers ([173,174], and The Cancer Genome Atlas (TCGA) data). This evidence concerns the gene HJURP and familial pancreatic carcinoma.