IFNA17 and Flavivirus Infections: Given the specific characteristics of exosomes and the presence of different proteins and RNAs, they can interact with the endothelial cells, inducing an alertness status in the endothelium and causing the activation and secretion of inflammatory mediators, such as TNF-α, INF-α, IL-6, IL-8, IL-10, IL-12p70, IP-10, and RANTES, establishing the first protective proinflammatory response during flavivirus infection [13].