INS and Insulin resistance: Some metabolites of phospholipid metabolism (lysophosphatidylcholine C18:2, acyl-alkyl-phosphatidylcholines, and glycine) were found in hyper-insulin-sensitivity cases whereas some phospholipid metabolism metabolites (e.g., diacyl-phosphatidylcholines, acyl-alkyl-phosphatidylcholines, sphingomyelin C16:1) were associated with insulin resistance and less insulin secretion.