The different metabolic profiles found here were correlated to an increased protein breakdown led by cachexia, counterbalanced by the improvement in food intake and increased muscle protein turnover in tumor-bearing adult offspring rats from a maternal leucine-rich diet, as showed by the activation of the mTOR pathway and the maintenance of muscle cathepsin H and calpain activities, described in our previous study [3]. This evidence concerns the gene MTOR and neoplasm.