Proteins involved in metabolic processes are mainly represented by groups of enzymes, ion channels, amino acid transporters, and subunits of G-proteins that regulate adenylate cyclase and phospholipase C. The set of enzymes contained in exosomes of glioma cells well reflects the characteristics of the metabolism of tumor cells, most of which catalyze various stages of glycolysis and are involved in the Warburg effect. Here, ADCY1 is linked to glioma.