This is evident as miR-1 is downregulated in breast cancer tissues when compared to normal tissues and re-expression of miR-1 suppresses tumor cell growth, migration, and metastasis and promotes apoptosis in vitro and in vivo via targeting of K-RAS and human metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) [83]. Here, KRAS is linked to breast carcinoma.