One possible caveat that could be associated with this study is the quantification of the expression levels of dysregulated miRNAs in total carcinoma tissue lysates of IBC and non-IBC, which may overlap with miRNAs derived from the infiltrated immune cells, particularly macrophages, as we and others have shown that IBC tumors are known to be a highly infiltrated with CD163+ M2-type tumor-associated macrophages [44]. Here, CD163 is linked to neoplasm.