Since we observed a poor statistical collinearity between the HDL-c and the LCAT concentration (Variation Inflation Factor (VIF) = 1.772 in a regression model setting LCAT as the independent variable and HDL-c as the dependent variable; VIF = 1.179 when setting HDL-c as the independent variable and LCAT as the dependent variable), we were thus prompted to investigate which was the most predictive parameter for faster CKD progression. The gene discussed is LCAT; the disease is chronic kidney disease.