LCAT and chronic kidney disease: Vice versa, 1 μg/mL reduction in LCAT concentration predicted by 0.78 with up to a 3.39 times higher risk of dialysis entry and/or creatinine doubling, even when HDL-c was included in the model among other co-variates (HR = 2.370 (1.278–4.396), p = 0.006) (Table S2), suggesting that a reduced LCAT concentration independently predicts faster CKD progression beyond the contribution of low HDL-c.