LCAT and chronic kidney disease: It is worth noting that reduced LCAT concentration specifically predicted faster CKD progression and worse disease-related prognosis, as a 1 μg/mL reduction in LCAT concentration was predictive of an increased risk of a composite outcome of all-cause mortality and faster CKD progression (HR = 1.742 (1.060–2.864), p = 0.029), while it was not predictive for all-cause mortality alone (HR = 1.058 (0.487–2.297), p = 0.887) or for the occurrence of cardiovascular fatal or non-fatal events alone (HR = 0.622 (0.366–1.057), p = 0.079) (Table S2).