INS and Hyperglycemia: Therefore, in line with this and previous studies, optimal glycemic control during COVID-19 infection may be protective against adverse events and should include the proper regulation of hyperglycemia (HbA1c < 7%; 53 mmol/mol), the avoidance of hypoglycemia and keeping blood glucose levels within a physiological range between 4.4–10 mmol/L during hospitalization and treatment with insulin [78].