INS and Hypoglycemia: A clinically important observation in this study was that, in patients with hyperglycemia, for every 0.56 mmol/L drop in plasma glucose level between admission and 18 days of hospitalization, there was an 11% relative decrease in severe disease risk; however, the authors recognize the importance of avoiding the risk of hypoglycaemia during glycemic control with insulin, according to earlier suggestions [96].