We examined the frequency of these cells (CD3+ CD8- IFN-γ− IL-17- GM-CSF+) among the overall Th cells and found a statistically significant increase in these cells in PBMC from MS patients after in vitro stimulation when compared to those from HCs (HCs n = 10, MS patients n = 9, p = 0.0009 unpaired t-test, Figure 1F). This evidence concerns the gene IFNG and myeloid sarcoma.