Moreover, we found that blocking either IL-2, IL-12, or both together significantly reduced the percentage of B cells expressing GM-CSF in MS but not in HC (Wilcoxon test, MS n = 7, blocking IL-2 p = 0.031; blocking IL-12 p = 0.046, blocking IL-2 + IL-12 p = 0.031; Wilcoxon test, HC n = 6, blocking IL-2 p = 0.06; blocking IL-12 p = 0.56; blocking IL-2 + IL-12 p = 0.093; Figure 7G,H). Here, CSF2 is linked to myeloid sarcoma.