In this regard, by a genomic analysis at the BALF cells of COVID-19 patients, Zhou et al. showed a high enrichment of ISG members belonging to the inflammatory regulation cluster which included neutrophil-recruiting mediators CXCL8, CXCL1, CXCL2, CXCL10, chemokine (C-C motif) ligand (CCL)2, CCL7 and other attractants of monocytes and immune cells CXCL6, CXCL11, CCL2, CCL3, CCL4, CCL7, CCL8, as well as STAT1 itself which, by positive feedback, leads to the persistence of the inflammatory status [59]. This evidence concerns the gene STAT1 and COVID-19.