Representative IHC stains, shown in Figure 1b, revealed low levels of BMP2 staining in the cytosol of normal nasopharyngeal epithelium (panel (i), white arrows), while in NPC, significantly higher levels of BMP2 were observed in the cytosol of tumour cells (panel (ii), white arrows); stromal tissue failed to stain for BMP2 (panel (ii), black arrows). This evidence concerns the gene BMP2 and nasopharyngeal carcinoma.