C9orf72 and amyotrophic lateral sclerosis: Interestingly the IR-based pathomechanism turned out to be relevant for other diseases with intronic GC-rich but not A/AT-rich microsatellite mutations including C9orf72-linked amyotrophic lateral sclerosis with frontotemporal dementia (C9-ALS/FTD) and Fuchs endothelial corneal dystrophy (FECD).